Trennung von guanidinverbindungen durch ionenaustauscher-dünnschichtchromatographie

✍ Scribed by A. Völkl; H.H. Berlet

• Publisher: Elsevier Science
• Year: 1975
• Tongue: English
• Weight: 582 KB
• Volume: 115
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(01)98951-4

✦ Synopsis

Thirteen guanidino compounds including glycocyamine, glycocyamidine, creatine, creatinine, arginine and guanidinosuccinic acid were chromatographed on thin-layer plates pre-coated with ion-exchange resins. Maximum resolution was obtained on layers of the cation-exchange resin eluted with 0.12 M sodium citrate buffer of pH 5.2, permitting the separation of nine of the thirteen guanidino compounds. Relationships between structure and physiochemical properties and the elution patterns of some selected guanidines were graphically evaluated.