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Treatment with C1 inhibitor concentrate in abdominal pain attacks of patients with hereditary angioedema

✍ Scribed by Konrad Bork; Gabriele Meng; Petra Staubach; Jochen Hardt


Book ID
109142892
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
189 KB
Volume
45
Category
Article
ISSN
0372-1248

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Hereditary angioedema (HAE) is caused by mutations in the C1 inhibitor gene (SERPING1, C1NH) and the result is C1 inhibitor deficiency, either in levels or function. We have searched exon 8 for mutations by direct sequencing and analyzed the rest of the exons by SSCP in 87 Spanish families affected