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Treatment of xenograft models of human malignant mesothelioma utilizing adenovirus-mediated gene therapy

✍ Scribed by Smythe, WR; Hwang, HC; Elshami, AA; Kucharkzuk, J; Amin, KA; Kaiser, LR; Albelda, SM


Book ID
123504067
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
142 KB
Volume
15
Category
Article
ISSN
0169-5002

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## Abstract ## Background Malignant mesothelioma is a highly aggressive tumor with poor prognosis. We hypothesized that the tumor‐specific midkine (Mdk) promoter could confer transcriptional targeting to oncolytic adenoviruses for effective treatment of malignant mesothelioma. ## Methods We anal