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Treatment of the T98G glioblastoma cell line with antisense oligonucleotides directed toward mRNA encoding transforming growth factor-α and the epidermal growth factor receptor

✍ Scribed by Marvin Rubenstein; Roberta Glick; Terry Lichtor; Yelena Mirochnik; Pauline Chou; Patrick Guinan


Book ID
111640824
Publisher
Springer US
Year
2001
Tongue
English
Weight
305 KB
Volume
18
Category
Article
ISSN
1357-0560

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Type beta transforming growth factor (B-TGF) is a potent growth inhibitor to many human tumor cell lines. Very little is known about the mechanism for this growth inhibitory action of B-TGF. We here report the effect of B-TGF on proliferation and epidermal growth factor receptor (R-EGF) expression i