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Treatment of soloid tumors and acute leukemias with the polyamine antimetabolites difluoromethylornithine and methylglyoxal bis (guanylhydrazone)

โœ Scribed by M. Garbrecht; S. Busch; T. Langenbuch; G. Ziemer


Book ID
112785295
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
135 KB
Volume
111
Category
Article
ISSN
1432-1335

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Treatment of acute myeloid leukemia and
โœ Jean-Albert Gastaut; Guy Tell; Paul J. Schechter; Dominique Maraninchi; Brynhild ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 419 KB

A combined eflornithine-MGBG treatment was studied in patients with acute myeloid leukemia (AML) or blastic transformation of chronic myeloid leukemia (BT CML). The first ten patients (5 AML, 5 BT CML) received i.v. or p.o. eflornithine 6 g m-2 day-1 and i.v. MGBG 500 mg/m2 once a week. The duration