Treatment of Severe Myasthenia Gravis with Protein A Immunoadsorption and Cyclophosphamide
β Scribed by Flachenecker, Peter; Taleghani, Behrouz Mansouri; Gold, Ralf; Grossmann, Ralf; Wiebecke, Dieter; Toyka, Klaus Viktor
- Book ID
- 122986398
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 55 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0955-3886
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Acute treatment of myasthenic crisis with immunoadsorption (IA) or plasma exchange is well established. The efficiency of chronic apheresis therapy in myasthenia gravis (MG), however, and its efficacy in reducing concomitant potentially harmful immunosuppressive therapy, is unknown. We treated 13 pa
## Abstract Twentyβthree myasthenia gravis (MG) subjects, mean (SD) age 41.6 years (14), showing poor disease control or steroidβrelated side effects, received treatment for 12 months with intravenous cyclophosphamide (CP; __n__ = 12) or placebo (PL; __n__ = 11) in a randomized, doubleβblind trial.