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Treatment of retinoblastoma. Results obtained from a prospective study of 51 patients

โœ Scribed by Marta Zelter; Angelica Damel; Guillermo Gonzalez; Laura Schwartz; Guillermo Gallo; Enrique Schvartzman; Federico Sackmann Muriel

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
660 KB
Volume
61
Category
Article
ISSN
0008-543X

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โœฆ Synopsis

During 4 years, 51 patients with retinoblastoma were studied (unilateral 32, and bilateral 19). Treatment consisted of enucleation of those eyes which showed massive involvement followed by radiotherapy when there was optic nerve and/or orbit involvement. Systemic chemotherapy was administered to all patients who underwent nonsurgical treatment and when the histologic examination showed choroidal optic nerve head and/or optic nerve involvement or residual tumor after enucleation. When there was compromise of the central nervous system intrathecal chemotherapy was administered. Nonsurgical treatment consisted of radiotherapy and/or light coagulation. Survival was 90.6% for unilateral cases and 84.2% for the bilateral. The median follow-up was 31 months and 29 months, respectively. Of 19 conservated eyeballs, 16 preserve useful vision (63%).

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