Treatment of relapsed or refractory acute promyelocytic leukemia
โ Scribed by Martin S. Tallman
- Book ID
- 119195362
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 128 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1521-6926
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๐ SIMILAR VOLUMES
Seventeen patients with relapsed or refractory acute nonlymphocytic leukemia were treated with 14 mg/m2 of mitoxantrone given in a 30-minute infusion daily for three days. If the day fourteen bone marrow showed residual leukemia, a second course was given at the same dose for two days. Eight patient
Background. All-trans retinoic acid (ATRA) is effective in the treatment of relapsed or refractory acute promyelocytic leukemia (APL), but relapse is the rule if response is unmaintained. Methods. Seventeen patients with APL were salvaged with ATRA at a dosage of 50 mg/mz/day for 3 months or until