Treatment of refractory severe aplastic anemia with granulocyte colony stimulating factor and interleukin 3
β Scribed by M. Schleuning; C. Thomssen; H.-J. Kolb; H.-J. Sauer; W. Wilmanns
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 284 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0361-8609
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To evaluate the therapeutic potential of hematopoietic growth factors (HGFs) during immunosuppressive treatment (IST) of severe aplastic anemia (SAA), 38 patients with newly diagnosed SAA received IST alone (group I), or IST plus recombinant human erythropoietin and granulocyte-macrophage colony-sti
## Abstract Recombinant human granulocyte colonyβstimulating factor (rhGβCSF) and erythropoietin (rhEPO) were used to treat patients with aplastic anemia (AA). In terms of effects on erythrocyte recovery, the combined use of rhGβCSF and rhEPO showed a favorable response in 6 of 14 (42.9%) patients