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Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component

✍ Scribed by Kondo, Yasuko; Koga, Shoji; Komata, Tadashi; Kondo, Seiji

Book ID
110062868
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
200 KB
Volume
19
Category
Article
ISSN
0950-9232

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Telomerase is a ribonucleoprotein that synthesizes telomeric DNA on chromosomal ends. While telomerase is undetectable in most normal somatic tissues, telomerase activation has been detected by a polymerase chain reaction (PCR)-based assay (TRAP) in many immortal cell lines and various cancers, incl