𝔖 Bobbio Scriptorium
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Treatment of pediatric brain tumors

✍ Scribed by Matthias Karajannis; Jeffrey C. Allen; Elizabeth W. Newcomb

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
85 KB
Volume
217
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

Over the past decades considerable advances have been made in neurosurgery, radiotherapy and chemotherapy resulting in improved survival and cure rates for children with brain tumors. Here we review four of the most common subtypes of pediatric brain tumors, low‐grade and high‐grade astrocytomas, medulloblastomas and ependymomas, highlighting their molecular features regarding their tumor biology, and promising potential therapeutic targets that may hold promise for finding new β€œmolecular targeted” drugs. Importantly, appropriate clinical trial design will play a critical role in the evaluation of new and novel treatment approaches for pediatric brain tumors. J. Cell. Physiol. 217: 584–589, 2008. Β© 2008 Wiley‐Liss, Inc.

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