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Treatment of outlet obstruction constipation in Parkinson’s disease with botulinum neurotoxin A

✍ Scribed by Alberto Albanese; Giuseppe Brisinda; Anna Rita Bentivoglio; Giorgio Maria

Book ID
119394119
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
78 KB
Volume
98
Category
Article
ISSN
0002-9270

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## Abstract Constipation, a frequent symptom in Parkinson's disease (PD), is probably caused by degeneration of the autonomic nervous system, particularly the myenteric plexus. Cisapride is a drug that causes increased release of acetylcholine in the myenteric plexus. In a pilot study, cisapride th