Treatment of methylmercury poisoning in the rat with sodium 2,3-dimercaptopropane-1-sulfonate: Influence of dose and mode of administration
โ Scribed by Bernard Gabard
- Book ID
- 119002294
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 533 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0041-008X
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๐ SIMILAR VOLUMES
The embryotoxic and teratogenic effects of methylmercury in experimental animals have been established by several investigators. The protective activity of 2,3-dimercaptopropanol (BAL) and sodium 2,3-dimercaptopropane-1-sulfonate (DMPS, a chelator used in the treatment of inorganic and organic mercu
The distribution and excretion of sodium 2,3-dimercapto-1,3 14C-propane-1-sulfonate as dependent on time has been studied in the rat. The highest concentration is found in the kidneys, the lowest in the brain. The excretion is very rapid (T1/2 = 19 min) and follows a monoexponential curve during the