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Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1

✍ Scribed by Hunder, Naomi N.; Wallen, Herschel; Cao, Jianhong; Hendricks, Deborah W.; Reilly, John Z.; Rodmyre, Rebecca; Jungbluth, Achim; Gnjatic, Sacha; Thompson, John A.; Yee, Cassian


Book ID
118023722
Publisher
Massachusetts Medical Society
Year
2008
Tongue
English
Weight
279 KB
Volume
358
Category
Article
ISSN
0096-6762

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## Abstract NY‐ESO‐1 is one of the most immunogenic cancer antigens eliciting strong humoral and cellular immune responses in patients with NY‐ESO‐1‐expressing malignancies. Since CD4+ T cells play a critical role in generating and maintaining antigen‐specific cellular and humoral immune responses,