## Background: The unsatisfactory control of neuroendocrine tumor growth with chemotherapy and/or interferon (ifn-2a) stimulated us to investigate the role of the somatostatin analogue octreotide (sms 201.995), which is reported to be highly effective in controlling carcinoid syndrome symptoms. oct
Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a: A study by the Italian trials in Medical Oncology Group
โ Scribed by Emilio Bajetta; Nicoletta Zilembo; Maria Di Bartolomeo; Angelo Di Leo; Silvana Pilotti; Anna Maria Bochicchio; Rita Castellani; Roberto Buzzoni; Luigi Celio; Luigi Dogliotti; Gabriella Pinotti; Enrico Aitini; Roberto Labianca; Adriano Fornasiero; Pietro Riva; Giuseppe Schieppati; Patrizia Nelli; Luigi Mariani
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 636 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0008-543X
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## Background: The objectives of the current study were: 1) to verify whether the addition of modulating low doses of interferon-2b (ifn) to 5-fluorouracil (5-fu) and levofolinic acid (1-fa) could improve clinical results in patients with advanced colorectal carcinoma; and 2) to evaluate the role o