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Treatment of massive pulmonary embolism with centrally administered tissue-type plasminogen activator

✍ Scribed by Subodh K Mohindra; George O Udeani


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
404 KB
Volume
22
Category
Article
ISSN
1097-6760

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✦ Synopsis


We report the use of centrally administered tissue-type plasminogen activator for three patients who presented with massive pulmonary embolism to the emergency department. In all patients, rapid improvement of pulmonary arterial pressures ensued by the end of the drug infusion, while the presenting symptoms of chest pain and shortness of breath subsided.


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Efficacy and tolerance of recombinant ti
✍ Spengel, F.A. ;KοΏ½ffer, G. ;Stiegler, H. πŸ“‚ Article πŸ“… 1993 πŸ› Springer-Verlag 🌐 English βš– 641 KB

The efficacy and safety of recombinant tissue-type plasminogen activator (rt-PA) was evaluated in 46 patients with thrombembolic arterial occlusions in leg arteries, rt-PA was given over 1-4 h with a maximum dose of 18 mg. The effect of rt-PA treatment was determined as patency of the occluded arter