Treatment of lupus-induced thrombocytopenia with recombinant human interleukin-11
β Scribed by Shamiram Feinglass; Atul Deodhar
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 88 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
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We investigated the effects of YM294, recombinant human interleukin-11, on changes in blood cell levels in carboplatin-treated rats. Continuous infusion of YM294 was carried out by either intravenous or subcutaneous injection (10 and 100 micrograms/rat/day) for 14 days via an implanted osmotic pump.
## Abstract ## BACKGROUND Previous research has shown oprelvekin (recombinant human interleukinβ11 [rhILβ11]) to be effective in reducing the requirements for platelet transfusions after myelosuppressive chemotherapy in patients who have previously experienced thrombocytopenia. The economic conseq