Lupus pernio, a form of cutaneous sarcoidosis usually affecting the face, is often disfiguring and resistant to therapies, both medical and surgical. To our knowledge, there have been no previous reports of laser therapy for this condition. We describe a case of nasal lupus pernio successfully manag
Treatment of lupus erythematosus with pulsed dye laser
✍ Scribed by Ofelia Baniandrés; Pablo Boixeda; Paulina Belmar; Alejandro Pérez
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 46 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background and Objectives
The treatment of cutaneous lupus erythematosus (CLE) with dye and argon laser has been evaluated in a number of articles in recent years. The improvement of telangiectasias and chronic erythema of the cutaneous lesions was based on the selective photothermolysis ablation of the dilated capillaries and venules.
Study Design/Materials and Methods
We describe the results of the treatment of cutaneous lesions of 14 patients; eight with discoid lupus erythematosus (DLE) and six with systemic lupus erythematosus (SLE). Three patients received a treatment with flashlamp pulsed dye laser (FPDL) (585 nm, 450 microseconds) with fluences in the range from 5 to 7.75 J/cm^2^; the other 11 patients were treated with long pulsed dye laser (LPDL) (595 nm, 1.5–10 milliseconds) with fluences in the range from 6 to 13 J/cm^2^ depending on the pulse duration.
Results
During a median follow‐up of 10 months, we observed an average improvement in over 60% of the lesions. A few side effects were observed in all patients: four had transient hyperpigmentation and one patient had light scarring. Three patients had a relapse after more than 1 year; they were then offered conventional treatment.
Conclusions
We confirm that pulsed dye laser is a good alternative treatment for the erythema in active cutaneous lesions of lupus erythematosus (LE). Lasers Surg. Med. 32:327–330, 2003. © 2003 Wiley‐Liss, Inc.
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