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Treatment of intractable rheumatoid arthritis with total lymphoid irradiation (TLI): immunological and clinical changes

โœ Scribed by Strober, Samuel; Field, Elizabeth M.; Kotzin, Brian L.; Hoppe, Richard T.; Engleman, Edgar C.; Tanay, Amir S.; Kaplan, Henry S.

Book ID
121999274
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
788 KB
Volume
1
Category
Article
ISSN
0167-8140

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Sustained improvement of intractable rhe
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โœ Elizabeth H. Field; Samuel Strober; Richard T. Hoppe; Andrei Calin; Edgar G. Eng ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 934 KB

Total lymphoid irradiation (TLI) was administered to 11 patients who had intractable rheumatoid arthritis that was unresponsive to conventional medical therapy, including aspirin, multiple nonsteroidal antiinflammatory drugs, gold salts, and D-penicillamine. Total lymphoid irradiation was given as a

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Twenty patients with intractable rheumatoid arthritis were treated with 750-rad or 2,000-rad lymphoid irradiation in a randomized double-blind comparative study. Over a 12-month followup period, there was a significant improvement in 4 of 7 and 6 of 7 standard parameters of disease activity followin