Treatment of hypophonia with collagen vocal cord augmentation in patients with parkinsonism

✍ Scribed by Amy N. Hill; Joseph Jankovic; Kevin D.A.T. Vuong; Don Donovan

• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 389 KB
• Volume: 18
• Category: Article
• ISSN: 0885-3185
• DOI: 10.1002/mds.10554

✦ Synopsis

Abstract

We conducted structured interviews of patients with Parkinson's disease (PD) and other parkinsonian disorders and their caregivers after augmentation of vocal folds with collagen injections. A total of 12 patients (mean age, 73.7 ± 8.6 years) completed the questionnaire after an average of 3.0 ± 1.7 collagen injections, with an average of 13.8 ± 7.4 weeks between each injection. In addition to improvement in all six voice quality questions, there was significant improvement (P < 0.05) in the Glascow Benefit Inventory (GBI) score. The injection procedure was tolerated well by patients with an average duration of benefit lasting 7.8 ± 8.5 weeks. Augmentation of vocal folds with collagen provides temporary improvement in voice in patients with parkinsonian hypophonia. © 2003 Movement Disorder Society