To assess the frequency and significance of complete resolution of inflammatory activity following corticosteroid therapy, 115 patients with severe HBsAg-negative chronic active hepatitis were followed regularly for 84 f 5 months. Of 83 patients eligible to revert to normal liver tissue, 18 did so a
Treatment of HBsAg-Positive chronic active hepatitis with corticosteroids and/or azathioprine
โ Scribed by Giuseppe Manzillo; Felice Piccinino; Evancelista Sagnelli; Crescenzo Maria Izzo; Giuseppe Pasquale; Giuseppe Maio; Pietro Filippini; Francesca Maria Felaco
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 429 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0940-5437
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๐ SIMILAR VOLUMES
## Eleven patients of Chinese origin experienced spontaneous reactivation of chronic active hepatitis B. Eight HBsAg-positive patients were followed for an average of 15 months prior to, while three others presented during reactivation. Fatigue, hepatomegaly and jaundice were frequent findings. El
out significant deterioration in liver function over the subsequent 12 months.
CAH based on established criteria (7) and evidence of liver disease for greater than 6 months, were included in this study. Age, sex, drug history, alcohol intake and predisposing factors to HBV infection were recorded.
Several drugs which react with DNA decrease hepatitis B viral (HBV) DNA polymerase activity in vitro. Because such an alteration of viral replication, if produced in patients with hepatitis B surface antigen (HBsAg)-positive chronic hepatitis, may lead to elimination of viral infection, we conducted