𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Treatment of fungal infections of the central nervous system

✍ Scribed by William E. Bell

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
590 KB
Volume
9
Category
Article
ISSN
0364-5134

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✦ Synopsis

Abstract

The recent development of new antifungal antimicrobials that can be administered in combination with amphotericin B or as alternatives to it has expanded the dimensions of treatment for fungal infections of the central nervous system. These disorders have acquired increasing importance as patients with malignant and other illnesses associated with immunosuppression survive longer and as renal transplantation is more widely applied. Amphotericin B has remained the most effective therapeutic preparation for most types of neurological fungal disease, although important roles for 5‐fluorocytosine, miconazole, and, more recently, ketoconazole are being recognized. Bell WE: Treatment of fungal infections of the central nervous system.

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## CRYPTOCOCCAL MENINGITIS Cryptococcosis is a fungal disease of humans and animals. The encapsulated yeast-like fungus is an opportunistic pathogen of debilitated or immunologically compromised individuals. Cryptococcus neoformans 1-5 is most commonly implicated, although infections with Cryptoco