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Treatment of essential thrombocythemia with special emphasis on leukemogenic risk

โœ Scribed by G. Finazzi; T. Barbui

Book ID
105990494
Publisher
Springer
Year
1999
Tongue
English
Weight
51 KB
Volume
78
Category
Article
ISSN
0939-5555

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โœ Nand, Sucha; Stock, Wendy; Godwin, John; Fisher, Susan Gross ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 417 KB ๐Ÿ‘ 2 views

In polycythemia Vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%. This risk has been estimated to be 1-5.9% with hydroxyurea (HU) therapy. When compared with historical controls, the risk with use of HU does not a