Treatment of collagen-induced arthritis with recombinant plasminogen-related protein B: a novel inhibitor of angiogenesis
โ Scribed by Koichiro Tanaka; Takeshi Morii; Lawrence Weissbach; Keisuke Horiuchi; Katsuhito Takeuchi; Yoshiaki Toyama; Hideo Morioka
- Book ID
- 106234029
- Publisher
- Springer Japan
- Year
- 2011
- Tongue
- English
- Weight
- 498 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0949-2658
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## Abstract ## Objective Following the demonstration that the stress protein, BiP, prevented induction of collagenโinduced arthritis (CIA) in HLAโDRB\*0101^+/+^ (HLAโDR1^+/+^) mice, we investigated the immunotherapeutic ability of BiP to suppress disease during the active phase of CIA in HLAโDR1^+
## Abstract ## Objective To investigate whether the soluble form of interleukinโ1 (ILโ1) receptor accessory protein (sILโ1RAcP), whose physiologic function remains to be established, can serve as a specific inhibitor of ILโ1 signaling in vitro, and to evaluate its applicability in collagenโinduced