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Treatment of chronic anal fissure with isosorbide dinitrate

โœ Scribed by Joseph Lysy; Yardena Israelit-Yatzkan; Mirna Sestiere-Ittah; Daniel Keret; Eran Goldin


Publisher
Springer
Year
1998
Tongue
English
Weight
511 KB
Volume
41
Category
Article
ISSN
0012-3706

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## Abstract ## Background Nitric oxide donors such as isosorbide dinitrate (ISDN) are considered the first choice of treatment for anal fissure. After reports of the successful treatment of such fissures with botulinum toxin, this randomized blinded trial compared botulinum toxin with ISDN in the