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Treatment of B cell malignancies in patients using 131I Lym-1

✍ Scribed by Chapman, J.D.; Preece, S.; Braunstein, B.; Höhne, A.; Nester, C.J.; Brueggemann, P.; Hutchins, S.


Book ID
121893656
Publisher
Elsevier Science
Year
1990
Weight
167 KB
Volume
26
Category
Article
ISSN
0277-5379

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Lym-I is a murine IgG2, monoclonal antibody (MAb) that is B-cell specific but has greater avidity for malignant B cells when compared with normal B lymphocytes. It was originally produced by immunizing mice with nuclei of cultured cells from a patient with Burkitt's lymphoma. Ten patients with progr