Treatment of askin rosai tumor—need for a more aggressive approach

✍ Scribed by P. M. Parikh; B. S. Charak; S. D. Banavali; S. H. Advani; T. K. Saikia; R. Gopal; A. M. Borces; R. F. Chinoy; P. B. Desai

• Book ID: 102439629
• Publisher: John Wiley and Sons
• Year: 1988
• Tongue: English
• Weight: 192 KB
• Volume: 39
• Category: Article
• ISSN: 0022-4790
• DOI: 10.1002/jso.2930390212

✦ Synopsis

Fifteen cases of histologically proven Askin Rosai tumor were treated at Tata Memorial Hospital over a period of 3 years. Patients included 12 men and three women. Clinical features included chest wall mass (14), pain (11). bony involvement (6), fever (4). dyspnoea (4), weight loss ( I ) , cough ( I ) , and hcmoptysis (I). Previously treated patients received different treatment protocols, which made evaluation difficult. Of our ten patients who have completed induction therapy, five received vincristine and cyclophosphamide, whereas the other five received more aggressive chemotherapy. Complete remission has been achieved in two and four of these patients, respectively. One patient in each group had recurrence of the disease, in both cases at the local site. Thus, from our preliminary data, we suggest that Askin Rosai tumor should be treated with complete surgical excision followed by an aggressive combination of chemotherapy and local radiotherapy.