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Treatment of anti-recombinant interferon-alpha 2 antibody positive CML patients with natural interferon-alpha

✍ Scribed by P. v. Wussow; D. Jakschies; M. Freund; R. Hehlmann; F. Brockhaus; H. Hochkeppel; M. Horisberger; H. Deicher

Book ID
114712360
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
647 KB
Volume
78
Category
Article
ISSN
0007-1048

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✍ Otto PrΓΌmmer; Delta-P Study Group πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 657 KB

Background. Prolonged therapy with interferon (IFN) may lead to the formation of IFN antibodies. Methods. Patients with renal cell carcinoma (n = 270) with advanced localized disease were randomized after complete tumor resection to receive treatment with adjuvant recombinant IFN-alpha-2a (rIFN-a2a