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Treatment of advanced ovarian cancer: A randomised trial comparing adriamycin or 4′epi-adriamycin in combination with cisplatin and cyclophosphamide

✍ Scribed by Bezwoda, W. R.


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
395 KB
Volume
14
Category
Article
ISSN
0098-1532

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✦ Synopsis


Fifty-one patients with ovarian cancer were tients with < 2 cm residual disease had sigentered in a randomised trial comparing treat-nificantly higher rate of complete remission rnent with cisplatin + adriamycin + cyclo-than those with > 2 crn residual disease. Carphosphamide (PAC) to cisplatin + 4'epi-diotoxicity was significantly less in the PECadriamycin + cyclophosphamide (PEC). Com-treated group (0/24) as compared with the plete response rates for the two treatment PAC-treated group (6127, x2 = 4.09, p < 0.05).