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Treatment of adjuvant arthritis with granulocyte-colony stimulating factor and peptide derived from heat shock protein 65

✍ Scribed by Andrea Brendolan; Masanori Higuchi; Richard Sibley; Samuel Strober


Book ID
114008235
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
424 KB
Volume
221
Category
Article
ISSN
0008-8749

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## Abstract Immunologic adjuvants are used to augment the immunogenicity of MHC class I–restricted peptide vaccines, but this effect has rarely been systematically evaluated in a clinical trial. We have investigated, in a phase I study, whether addition of the 2 adjuvants GM‐CSF and KLH can enhance