## Abstract ## BACKGROUND. Acute myeloid leukemia (AML) carries a dismal prognosis in older patients. In this study, the authors evaluated the safety and efficacy of arsenic trioxide combined with lowβdose cytarabine in untreated patients aged β₯60 years with AML. ## METHODS. In a phase 1/2 desig
Treatment of acute myeloid leukemia in the elderly with low-dose cytarabine, hydroxyurea, and calcitriol
β Scribed by Christopher A. Slapak; Jane F. Desforges; Terry Fogaren; Dr. Kenneth B. Miller
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 571 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
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Fifty-four patients representing all the cases of acute myeloid leukemia in patients aged over 60 years, presenting to three adjacent hospitals, were studied. Only 26 of the 54 patients were considered suitable for remission induction with intensive combination chemotherapy which produced seven comp
## Abstract As sensitization of leukemic cells with granulocyte colonyβstimulating factor (Gβcsf) can enhance the cytotoxicity of chemotherapy in acute myeloid leukemia (AML), a pilot study was conducted in order to evaluate the effect of Gβcsf priming combined with lowβdose chemotherapy in patient