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Treatment failure and resistance with direct-acting antiviral drugs against hepatitis C virus

โœ Scribed by Jean-Michel Pawlotsky


Book ID
102241566
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
255 KB
Volume
53
Category
Article
ISSN
0270-9139

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The efficacy of specifically targeted anti-viral therapy for hepatitis C virus (HCV) (STAT-C), including HCV protease and polymerase inhibitors, is limited by the presence of drugspecific viral resistance mutations within the targeted proteins. Genetic diversity within these viral proteins also evol