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Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation

✍ Scribed by J. KIENAST; M. JUERS; C. J. WIEDERMANN; J. N. HOFFMANN; H. OSTERMANN; R. STRAUSS; H-O. KEINECKE; B. L. WARREN; S. M. OPAL; THE KYBERSEPT INVESTIGATORS

Book ID: 109149315
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 152 KB
Volume: 4
Category: Article
ISSN: 1538-7933
DOI: 10.1111/j.1538-7836.2005.01697.x

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In several animal experiments, high doses of antithrombin 111 concentrates have shown beneficial effects on mortality and reversal of coagulation abnormalities which had resulted from disseminated intravascular coagulation. Other experiments have suggested that antithrombin 111 infusion without hepa