The conformational entropy is the largest unfavorable effect that must be overcome during protein folding and binding. Accurate predictions of protein stability and binding affinity require a precise way of evaluating conformational entropy changes. Previously we implemented a computational approach
β¦ LIBER β¦
Treating Entropy and Conformational Changes in Implicit Solvent Simulations of Small Molecules
β Scribed by Mobley, David L.; Dill, Ken A.; Chodera, John D.
- Book ID
- 118231722
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 200 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0022-3654
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