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Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation

✍ Scribed by Hui-li Liu; Gang Zhao; Kui Cai; Hai-hua Zhao; Li-de Shi


Book ID
116286216
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
578 KB
Volume
218
Category
Article
ISSN
0166-4328

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## Abstract Some studies suggest that the histaminergic system plays an important role in learning and memory. However, the results seem to be controversial in many behavioral tasks. In the present study, we used HDC knockout (HDC‐KO) mice to investigate the effects of long‐term histamine deficienc