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Trapping and Structural Elucidation of an Intermediate in the Macrophomate Synthase Reaction Pathway

✍ Scribed by Serafimov, Jörg M.; Westfeld, Thomas; Meier, Beat H.; Hilvert, Donald


Book ID
125888093
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
85 KB
Volume
129
Category
Article
ISSN
0002-7863

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Trapping and structure determination of
✍ A. Gambacorta; R. Nicoletti; S. Cerrini; W. Fedeli; E. Gavuzzo 📂 Article 📅 1978 🏛 Elsevier Science 🌐 French ⚖ 268 KB

2,5-dialkyl pyrroles react in protic media with dichlorocarbene generated under basic conditions giving rise to ring expansion products (2,6-dialkyl-3chloropyridines) and addition products (2,5-dialkyl-2-dichloromethyl-2H-pyrl roles or Plancher's pyrrolenines) . The latter are not intermediates for