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Transynaptic modulation by insulin-like growth factor I of dendritic spines in Purkinje cells

✍ Scribed by M.P Nieto-bona; L.M Garcia-segura; I Torres-alemán


Book ID
117563816
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
407 KB
Volume
15
Category
Article
ISSN
0736-5748

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✍ M. P. Nieto-Bona; S. Busiguina; Dr. I. Torres-Aleman 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 641 KB

Recent evidence suggests that Purkinje cells are specific targets of insulin-like growth factor I (IGF-I) through their entire life span. During development, Purkinje cell numbers and their calbindin-28kD content increase after IGF-I treatment in culture. In the adult, part of the IGF-I present in t