Transynaptic effect of neonatal axon section on bouton appearance about somatic motor cells
✍ Scribed by Melvin Schadewald
- Publisher
- John Wiley and Sons
- Year
- 1942
- Tongue
- English
- Weight
- 406 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0021-9967
No coin nor oath required. For personal study only.
✦ Synopsis
INTRODUCTION AND HISTORY
Barnard ('40) has reported that section of the ventral roots of spinal nerves of adult cats results in a disappearance within a short time of the bouton terminaux (synaptic terminals) which end on ventral horn cells. This contention disputes the earlier findings of Lawrentjew ('34) in sympathetic ganglia and the subsequent results of Barr ('40) and Schadewald ( '41) who could detect no serious alteration in these structures about somatic motor cells even when a longer period of reaction was allowed after axon section. Quantitative estimates and statistical analysis by these latter two authors showed that no constant or progressive change of appreciable magnitude occurred which could not be more plausibly explained by the variability in number and appearance of these structures. Their results were in relatively close agreement despite the fact that different cell groups of the somatic motor system were studied. In a more recent communication Acheson, Lee, and Morison ('42) have not only shown that section of the phrenic nerve causes no detectable disturbance in bouton arrangement in the phrenic nucleus within 220 days, but they have also shown that only a transitory loss of function occurs which is chronologically correlated The material used in this study was obtained in part from the Department of Anatomy of the University of Minnesota with the permission and help of Prof. A. T. Rasmussen and in part also from the Department of Anatomy of the West Virginia. School of Medicine with the permissioii of Prof. S. B. Chandler.