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Transvaginal sonography of the yolk sac in normal and abnormal pregnancy

✍ Scribed by Stampone, C.; Nicotra, M.; Muttinelli, C.; Cosmi, E. V.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 718 KB
Volume: 24
Category: Article
ISSN: 0091-2751
DOI: 10.1002/(sici)1097-0096(199601)24:1<3::aid-jcu1>3.0.co;2-n

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✦ Synopsis

A cross-sectional study comprising 117 consecutive first trimester singleton pregnancies was performed using transvaginal sonography (TVS) to evaluate size abnormalities of the secondary yolk sac (YS) vis-a-vis pregnancy outcome. In normal pregnancy outcome (NPO) the YS diameter showed an increase from the 5th to the 11th week, menstrual age, followed by a decrease and its disappearance after 12 weeks, A YS of abnormal size was statistically significant ( p < 0.001) in spontaneous abortion (SA) versus NPO, with a sensitivity of 68.7%, a specificity of 99%, a positive predictive value of 91.6% and a negative predictive value of 95.2%. These preliminary results indicate that a measurement of the YS very early in gestation may be a useful marker of pregnancy outcome. 0

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