The absorption of water from the rat small intestine during drug absorption experiments was studied. The data indicated that approximately 4 ml. of water was lost from the intestine during 60 min. Keyphrases 0 Drug absorption4oncurrent loss of water, in rat intestine Water absorption, rat intestin
Transporters in the intestine limiting drug and toxin absorption
โ Scribed by R. P. J. Oude Elferink; R. de Waart
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 598 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1138-7548
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๐ SIMILAR VOLUMES
Drug transport in intestine, liver and kidney is similar, because in each case transport occurs across a barrier of epithelial cells. However, the physiological conditions differ in each organ: intestinal drug absorption is largely influenced by physicochemical conditions in the intestinal lumen; ac
The effect of metoclopramide on the absorption of drugs in solution in the small intestinal lumen of rats in situ was studied. Metoclopramide in doses up to 50 mg/kg sc did not significantly modify the disappearance of isoniazid and quinidine from the small intestinal lumen. At the end of the absorp