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Transporter associated with antigen-processing (TAP) genes and susceptibility to tuberculoid leprosy and pulmonary tuberculosis

✍ Scribed by R. Rajalingam; D. P. Singal; N. K. Mehra


Book ID
110890614
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
408 KB
Volume
49
Category
Article
ISSN
0001-2815

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Stable cell surface presentation of HLA class I molecules requires active transport of antigenic peptides across the endoplasmic reticulum by products of two genes, TAP1 and TAP2, which map in the major histocompatibility complex class II region. Alleles of each gene are derived from a combination o