Transport processes in pharmaceutical systems

✍ Scribed by Gordon L Amidon; Ping I Lee; Elizabeth M Topp

• Publisher: M. Dekker
• Year: 2000
• Tongue: English
• Leaves: 724
• Series: Drugs and the pharmaceutical sciences, v. 102
• Category: Library

✦ Synopsis

An explanation of pharmaceutical transport phenomena. It demonstrates applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, and whole body kinetics to drug release from polymer reservoirs and matrices.

✦ Table of Contents

Content: Preface; Contents; Contributors; Principles of Mass Transfer; Analytical Solutions to Mass Transfer; Pharmacokinetics: Model Structure and Transport Systems; Experimental Methods to Evaluate Diffusion Coefficients and Investigate Transport Processes of Pharmaceutical Interest; Dissolution of Pharmaceuticals in Simple and Complex Systems; Biological Transport Phenomena in the Gastrointestinal Tract: Cellular Mechanisms; Improving Oral Drug Transport via Prodrugs; Quantitative Approaches to Delineate Passive Transport Mechanisms in Cell Culture Monolayers.
Abstract:

Explains pharmaceutical transport phenomena. This book focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems. It demonstrates applications like drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes and others. Read more...