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Transport of the neutral form of amphiphilic drugs through a planar bilayer lipid membrane: The role of the pH gradient

โœ Scribed by V.V. Cherny; M.V. Simonova; V.S. Sokolov; V.S. Markin


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
575 KB
Volume
23
Category
Article
ISSN
1567-5394

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๐Ÿ“œ SIMILAR VOLUMES


Liposome transport of hydrophobic drugs:
โœ Vijay Joguparthi; Tian-Xiang Xiang; Bradley D. Anderson ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 334 KB

The design of liposomal delivery systems for hydrophobic drug molecules having improved encapsulation efficiency and enhanced drug retention would be highly desirable. Unfortunately, the poor aqueous solubility and high membrane binding affinity of hydrophobic drugs necessitates extensive validation