Transport of pipecolic acid in adult and developing mouse brain
β Scribed by Jang Soo Kim; Ezio Giacobini
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 560 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0364-3190
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## Abstract Summary: The neuronβspecific rat enolase (NSE) promoter was employed to establish transgenic mice expressing Cre recombinase in the central nervous system. Founders were crossed with dormant lacZ indicator mice and specificity as well as efficiency of Creβmediated transgene activation w
Cadaverine and pipecolic acid metabolism was investigated in vitro in several organs of the mouse by measuring 14CO2 formation from labeled precursors. The liver showed the highest formation of 14CO2 from [1,5-14C]-cadaverine, whereas brain demonstrated a much lower formation. Anaerobiosis or inhibi