𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Transport of Phosphatidylcholine in MDR3-Negative Epithelial Cell Lines via Drug-Induced MDR1 P-Glycoprotein

✍ Scribed by Abedel-nasser Ghazi Abulrob; Mark Gumbleton


Book ID
115584221
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
109 KB
Volume
262
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


A novel MDR1 G1199T variant alters drug
✍ Matthew H. Crouthamel; Daniel Wu; Ziping Yang; Rodney J.Y. Ho πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 227 KB

The human multidrug resistance gene MDR1 encodes the protein product P-glycoprotein (P-gp). P-gp is an integral membrane protein which mediates ATP-dependent substrate efflux. We recently discovered a novel G --> T variant at 1199 nucleotide position of MDR1 which exhibits a 2.3% allelic frequency i

Cytogenetic and molecular characterizati
✍ Turid Knutsen; Lyn A. Mickley; Thomas Ried; Eric D. Green; Stanislas du Manoir; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 835 KB

Drug resistance, both primary and acquired, is a major obstacle to advances in cancer chemotherapy. In vitro, multidrug resistance can be mediated by P-glycoprotein (PGY1), a cell surface phosphoglycoprotein that acts to efflux natural products from cells. PGY1 is encoded by the MDR1 gene located at