Transport of folic acid across Caco-2 cells is more effective than 5-methyltetrahydrofolate following the in vitro digestion of fortified bread

Development of a three-tier in vitro sys

Development of a three-tier in vitro system, using Caco-2 cells, to assess the effects of lactate on iron uptake and transport from rye bread following in vitro digestion

✍ Stine Bering; Klaus Bukhave; Marianne Henriksen; Brittmarie Sandström; Sandra Pa 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB 👁 1 views

## Abstract A three‐tier Caco‐2 cell system was developed to assess simultaneously iron dialysability, uptake and transport across the Caco‐2 monolayer from an __in vitro__ digested food matrix. The effect of lactate (0–200 mmol L^−1^) on iron absorption from rye bread subjected to simulated peptic