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Transport characteristics of rutin deca (H-) sulfonate sodium across Caco-2 cell monolayers

✍ Scribed by Ying He; Su Zeng


Book ID
111770389
Publisher
Pharmaceutical Press
Year
2005
Tongue
English
Weight
184 KB
Volume
57
Category
Article
ISSN
2042-7158

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The objective of this study was to investigate the mechanisms by which berberine is transported in the secretory and absorptive directions across Caco-2 cell monolayers. The basolateral-to-apical (B-A) flux was 30-fold greater than the apical-to-basolateral flux and temperature dependent (i.e., dras