Transport and in vivo elimination of cysteinyl leukotrienes
✍ Scribed by Dietrich Keppler; Michael Müller; Cornelia Klünemann; Albrecht Guhlmann; Katja Krauss; Juliane Müller; Ulrike Berger; Inka Leier; Ertan Mayatepek
- Book ID
- 118372200
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 469 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0065-2571
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Keppler D. ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane: role of the ATP-dependent transport system for glutathione S-conjugates.
N-Acetyl-leukotriene E4 has been identified as an endogenous, biologically less active cysteinyl leukotriene metabolite in rodents and humans. To evaluate the ratio of hepatobiliary to renal elimination of leukotrienes noninvasively by positron emission tomography (PET), we synthesized N-["Clacetyl-