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Transplanted neural precursor cells reduce brain inflammation to attenuate chronic experimental autoimmune encephalomyelitis

✍ Scribed by Ofira Einstein; Nikolaos Grigoriadis; Rachel Mizrachi-Kol; Etti Reinhartz; Eleni Polyzoidou; Iris Lavon; Ioannis Milonas; Dimitrios Karussis; Oded Abramsky; Tamir Ben-Hur

Book ID: 116458683
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 516 KB
Volume: 198
Category: Article
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2005.11.007

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Transplanted neural precursor cells remyelinate efficiently acutely demyelinated focal lesions. However, the clinical value of cell transplantation in a chronic, multifocal disease like multiple sclerosis will depend on the ability of transplanted cells to migrate to the multiple disease foci in the