Transplantation: Pre-emptive CMV therapy versus universal CMV prophylaxis in renal transplant recipients
โ Scribed by Kelsey, Rebecca
- Book ID
- 115545856
- Publisher
- Nature Publishing Group
- Year
- 2012
- Tongue
- English
- Weight
- 181 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1759-5061
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## Abstract Cytomegalovirus is a significant cause of morbidity and mortality in transplantation. Controversy exists concerning whether prophylactic or preโemptive therapy is the optimal strategy for preventing CMV disease. In addition, CMV impacts the transplanted graft, transplant recipient and t
## Abstract Preโemptive therapy (PET) initiated on the basis of HCMV positivity in the blood using sensitive methods such as PCR, nucleic acid sequence based amplification or antigenaemia offers several advantages for the management of HCMV infection. These include the ability to target antiviral d